My way of classifying Israel geographically is very crude. Roughly Israel can be divided into three. The green fertile northern region includes Galilee and Golan; with Haifa and Netanya the major cities.
The political, scientific and religious hub of Israel is the central region where you have Jerusalem and Tel Aviv.
However, where I reside is the southern part called Negev which has Beer Sheva and Eilat as major cities.